全文获取类型
收费全文 | 155665篇 |
免费 | 11582篇 |
国内免费 | 4177篇 |
专业分类
耳鼻咽喉 | 1199篇 |
儿科学 | 2999篇 |
妇产科学 | 1970篇 |
基础医学 | 8417篇 |
口腔科学 | 3099篇 |
临床医学 | 21039篇 |
内科学 | 20708篇 |
皮肤病学 | 2337篇 |
神经病学 | 10423篇 |
特种医学 | 15050篇 |
外国民族医学 | 39篇 |
外科学 | 14687篇 |
综合类 | 21005篇 |
现状与发展 | 23篇 |
一般理论 | 2篇 |
预防医学 | 5691篇 |
眼科学 | 2158篇 |
药学 | 11048篇 |
84篇 | |
中国医学 | 11155篇 |
肿瘤学 | 18291篇 |
出版年
2024年 | 351篇 |
2023年 | 2535篇 |
2022年 | 4933篇 |
2021年 | 6549篇 |
2020年 | 6145篇 |
2019年 | 5249篇 |
2018年 | 5275篇 |
2017年 | 5939篇 |
2016年 | 6428篇 |
2015年 | 6053篇 |
2014年 | 11005篇 |
2013年 | 13040篇 |
2012年 | 9154篇 |
2011年 | 9856篇 |
2010年 | 8239篇 |
2009年 | 7699篇 |
2008年 | 7610篇 |
2007年 | 7932篇 |
2006年 | 7033篇 |
2005年 | 6313篇 |
2004年 | 5151篇 |
2003年 | 4404篇 |
2002年 | 3457篇 |
2001年 | 3244篇 |
2000年 | 2791篇 |
1999年 | 2208篇 |
1998年 | 1889篇 |
1997年 | 1642篇 |
1996年 | 1382篇 |
1995年 | 1247篇 |
1994年 | 959篇 |
1993年 | 770篇 |
1992年 | 720篇 |
1991年 | 618篇 |
1990年 | 506篇 |
1989年 | 423篇 |
1988年 | 404篇 |
1987年 | 335篇 |
1986年 | 275篇 |
1985年 | 314篇 |
1984年 | 253篇 |
1983年 | 184篇 |
1982年 | 182篇 |
1981年 | 183篇 |
1980年 | 145篇 |
1979年 | 129篇 |
1978年 | 70篇 |
1977年 | 45篇 |
1976年 | 52篇 |
1975年 | 39篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
51.
目的分析激光消毒根管,防治根管治疗期间急症(endodonticinterappointmentemergencies,EIAE)发生的效果。方法慢性根尖周炎、慢性牙髓炎、牙髓坏死患者189例,随机分为激光组94例和对照组95例。激光组用激光消毒根管后一次性完成根管治疗;对照组直接行一次性完成根管治疗。对激光防治EIAE的效果进行临床评估。结果EIAE的发生率激光组为9.6%,对照组为35.8%,两组比较差异有显著意义(P<0.01)。结论运用激光消毒根管能有效地预防和降低根管治疗期间急症的发生。 相似文献
52.
妊娠期糖尿病62例临床分析 总被引:1,自引:0,他引:1
目的 探讨妊娠期糖尿病的合理处理及预后.方法 选择62例妊娠期糖尿病患者进行回顾性分析.结果 妊娠期糖尿病62例,其中单纯饮食控制17例,饮食控制 胰岛素治疗43例,2例未治疗.剖宫产42例,阴道产20例.合并妊高症3例,羊水过多2例,羊水过少4例,羊水栓塞1例,早产5例,高胆红素血症3例,真性红细胞增多症2例,死胎2例,新生儿窒息4例,新生儿畸形1例.结论 对妊娠合并糖尿病的孕妇进行早期的诊断及治疗,选择合适的时间及方式终止妊娠可以减少母儿并发症的发生率. 相似文献
53.
慢性肺心病哮喘持续状态218例临床分析 总被引:1,自引:0,他引:1
目的探索治疗慢性肺心病哮喘持续状态的方法。方法回顾性分析1983年10月~2005年3月收治的218例慢性肺心病哮喘持续状态患者的临床资料。结果哮喘持续状态在48h以内被控制的62例(28.4%);在72h以内控制的56例(25.7%);在120h以内控制的25例(11.5%);在168h以内控制的34例(15.6%);痊愈出院177例(81.2%);死亡41例(18.8%)。结论(1)治疗慢性肺心病哮喘持续状态.根据患者的病理变化.综合治疗.效果显著。(2)在治疗过程中.要恰当选择抗生素和平喘药;对那些血液黏滞度增高的患者.要加用血液稀释疗法。(3)测定血液黏滞度和氧饱和度.可以指导治疗、估计预后.应当列为常规检查。 相似文献
54.
良性阵发性位置性眩晕的自我治疗 总被引:14,自引:2,他引:12
目的比较改良的Epley耳石复位法(MEP)和改良的Semont耳石复位法(MSM)用于后半规管良性阵发性位置性眩晕(PC-BPPV)自我治疗的疗效。方法对2001年7月至2003年6月间的70例PC-BPPV患者分别使用MEP和MSM法进行自身治疗,1周后比较两组缓解率和治疗的副作用。结果MEP组中95%(n=37)患者完全缓解,而MSM组仅为58%(n=33,P〈0.001)。MSM组中,治疗的失败与动作执行的不准确密切相关。两组治疗有关的副作用差异无统计学意义。结论MEP比MSM能更有效的缓解PC-BPPV,MEP应为患者自身治疗的首选方法。 相似文献
55.
Anne-Catherine Bachoud-Lévi Philippe Hantraye Marc Peschanski 《Movement disorders》2002,17(3):439-444
Intrastriatal transplantation of striatal neuroblasts from human fetuses is a promising approach for treatment of Huntington's disease, on the basis of many experimental animal studies and, most recently, pilot clinical trials. Technically, several issues remain to be resolved (e.g., the precise site of dissection of the fetal tissue; the number and location of the fetal striatal implants; or the use of immunosuppressive therapy), and await larger-scale trials and purposely designed protocols. Further clinical data must also be obtained, and preliminary promising results must be replicated in a patient group large enough to provide conclusive results. It is important to establish (1) the amount of clinical benefit provided to the patient by the grafted cells; (2) the anticipated duration of clinical benefits; and (3) the secondary rate of decline after the benefit of the graft has been overbalanced. Evaluation of these parameters will require very long-term follow-up of the patients involved, over several years after grafting, before the technique can eventually be proposed widely to patients. 相似文献
56.
A. Al Tahan S. Arora A. Alzeer F. Al Tahan T. Malabarey A. Daif 《European journal of neurology》1997,4(1):52-58
The diagnosis of acute disseminated encephalomyelitis (ADEM) is frequently missed or delayed with consequent delay in instituting therapy in the crucial phase of the illness. The role of MRI in the diagnosis of ADEM is well established, however, the value of its early utilization of treatment on the outcome of patients has not been adequately stressed. Three patients with ADEM are described. Delay in the diagnosis of the first was associated with severe sequelae, while in the other two early diagnosis and institution of corticosteroid therapy which was facilitated by MRI, was associated with a better outcome. MRI should be carried out early once the diagosis of ADEM is entertained. 相似文献
57.
Localized proton magnetic resonance spectroscopy of a cerebellar tumor in a two-year-old child 总被引:1,自引:0,他引:1
B. Wilken G. Helms H. J. Christen J. Bhnk J. Frahm F. Hanefeld 《Child's nervous system》1996,12(10):626-629
Noninvasive localized proton magnetic resonance spectroscopy (MRS) was used for differential diagnosis of a focal brain lesion in a 2.5-year-old girl. The clinical signs were a mild head tilt and neck pain. Magnetic resonance imaging (MRI) revealed a lesion in the right hemisphere of the cerebellum, but its nature remained obscure. In this lesion quantitative determinations of cerebral metabolites by fully relaxed, short-echo-time proton MRS revealed markedly lowered N-acetylaspartate (NAA) and pronounced elevations of choline-containing compounds (Cho) and myo-inositol (Ins), whereas metabolite concentrations in cortical gray matter and white matter were within normal ranges. The metabolite pattern of the lesion indicated loss of vital neuroaxonal tissue (low NAA) and enhanced glial proliferation (high Cho and Ins), which, together with the MRI morphology, suggested a brain tumor. The diagnosis was established by neurosurgical exploration and total extirpation of the tumor. Histology confirmed an astrocytoma (WHO II). After 2 weeks' recovery the child was discharged with no neurological signs. 相似文献
58.
Changes on serial assessments of brain MRI lesion load are used for monitoring therapeutic efficacy in patients with multiple
sclerosis (MS). We assessed the accuracy and reliability of conventional spin-echo (CSE) and fast spin-echo (FSE) sequences
for measurement of lesion volume using a semiautomated contour technique. Cranial CSE and FSE examinations of 18 patients
with secondary progressive MS were studied. The mean lesion load was slightly higher with the CSE sequence (p = 0.002). Intraobserver
variability was significantly higher for FSE than for CSE, according to both the coefficient of variation between two measurements
(mean 2.48 % and 1.35 % respectively, p < 0.05) and back-transformed 95 % limits of agreement (1.005–1.060 for FSE; 0.988–1.019
for CSE). Although FSE sequences are quicker and the total lesion volume measurements are similar to those obtained with CSE,
the poorer reproducibility raises doubts about the use of FSE to replace CSE in clinical trials.
Received: 26 March 1996 Accepted: 4 April 1996 相似文献
59.
A. Heinig S. H. Heywang-Köbrunner P. Viehweg D. Lampe J. Buchmann R. P. Spielmann 《Der Radiologe》1997,37(9):710-717
Summary
Early recognition of recurrence and work-up of clinically indeterminate lesions may be impaired after reconstruction with
silicone implants due to superimposition of the implant or to scarring. This study was undertaken to evaluate the use of contrast-enhanced
MRI in patients with silicone implant after breast cancer. Contrast-enhanded MRI was offered to 169 patients. Comparative
two- to three-view mammography was also performed in 169 patients, as well as comparative sonography in 144 patients. Conventional
imaging and clinical examination detected only 8/13 recurrences, whereas 12/13 were detected by MRI. One recurrence had been
visible as a strongly enhancing 2-mm dot in a previous examination (2 years before), but was not called. It was therefore
counted as false negative. In addition, multicentricity was detected by MRI alone in two of three cases. MRI correctly diagnosed
scar tissue in all cases with indeterminate findings. However, due to false-positive calls caused by enhancing granulomas
specificity could not be improved. Contrast-enhanded MRI allowed decisive additional information in our study group and improved
the sensitivity significantly (concerning all diagnoses). Contrast-enhanded MRI is recommended in patients with diagnostic
problems or high risk of recurrence after silicone implants.
相似文献
60.
While the benefits of training manuals can hardly be questioned, they are exceedingly limited in reducing variability attributed to the "therapist factor." We propose that manuals provide a useful outline of the general principles of a therapeutic approach, but can only reduce therapist variability at the expense of other essential therapeutic phenomena. Manuals cannot adequately convey, for example, how the effective therapist functions as a model of adult living and as a person who provides guidance. We suggest that such an experience cannot readily be packaged in manualized form, though manuals may serve as a useful beginning. Recommendations for therapist manualized training include greater attention to the subtleties of human relationships and adequately conveying that any technique is effective only when catalysed by a living, relational process. 相似文献